منابع مشابه
Circulating microRNAs in aging
Aging research is currently focusing on circulating functional markers that can help discriminate the mechanisms of physiological aging from those of agerelated diseases (ARDs). The cellular model of choice for this type of studies, cell senescence, has been providing highly valuable information. Senescent cells are characterized by permanent cell cycle arrest and acquisition of a senescence-as...
متن کاملmiRandola: Extracellular Circulating MicroRNAs Database
MicroRNAs are small noncoding RNAs that play an important role in the regulation of various biological processes through their interaction with cellular messenger RNAs. They are frequently dysregulated in cancer and have shown great potential as tissue-based markers for cancer classification and prognostication. microRNAs are also present in extracellular human body fluids such as serum, plasma...
متن کاملCirculating microRNAs in Cardiovascular Diseases.
Cardiovascular Diseases (CD) are currently one of the most common causes of death. Because heart related deaths occur on such an enormous scale this phenomenon is referred to as an epidemic. Chronic and acute injury of the heart could be an effect of cardiac remodeling, which is a result of molecular, cellular and interstitial changes, influenced by hemodynamic load or neurohormonal activation ...
متن کاملCirculating MicroRNAs in cardiovascular disease.
MicroRNAs (miRNAs) are short, single-stranded, noncoding, highly conserved posttranscriptional regulators found in a variety of tissues including circulating blood.1 MicroRNAs regulate gene expression posttranscriptionally through inhibiting translation from and/or inducing degradation of specific RNAs.2 Certain miRNAs are expressed and function cell-type specifically or in association with par...
متن کاملCirculating microRNAs in patients with intracranial aneurysms
INTRODUCTION We compared circulating microRNA (miRNA) levels in plasma of patients with intracranial aneurysms (IA) to those of controls as a first step towards finding potential biomarkers for individuals at high risk of IA development and its subsequent rupture. PATIENTS AND METHODS Using a PCR array we measured 370 miRNAs in plasma of 15 patients with prior aneurysmal subarachnoid hemorrha...
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ژورنال
عنوان ژورنال: Stroke
سال: 2021
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.120.033688